Pentobarbital will decrease the level or effect of alfentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of atogepant by affecting hepatic/intestinal enzym... https://tetrabookmarks.com/story20335073/un-imparziale-vista-pentobarbital-rat-euthanasia