Compared with other good allosteric modulators that enhance ligand binding, benzodiazepine binding functions for a positive allosteric modulator by increasing the overall conduction of chloride ions throughout the neuronal cell membrane when GABA is presently bound to its receptor. This amplified chloride ion influx hyperpolarizes the neuron's membrane potential. https://caidenfsagn.newbigblog.com/42293877/the-2-minute-rule-for-benzodiazepines-uses