Here, we demonstrate that conolidine, a natural analgesic alkaloid Utilized in conventional Chinese drugs, targets ACKR3, thus supplying supplemental evidence of the correlation between ACKR3 and ache modulation and opening alternative therapeutic avenues for the cure of Serious discomfort. Conolidine is an indole alkaloid derived within the bark with https://kirkf284exq3.cosmicwiki.com/user