This methylation profile is already acquired with the MBL stage3 and continues to be somewhat secure eventually. Nevertheless, some CLL have intratumor variability in specified locations, which can alter the expression of many genes and facilitate tumor evolution.71 Of note, this variability is greater in U-CLL than in M-CLL and https://situsjudimbl7709977.creacionblog.com/32183100/the-smart-trick-of-mbl77-that-nobody-is-discussing